3-O-Benzyl-1,2;5,6-Di-O-Isopropylidene-a-D-Glucofuranose

Molecular Formula: C₁₉H₂₆O₆

Molecular weight: 350.4061

CAS No.: 18685-18-2

Molecular structure:

Characteristics: This product is a sticky liquid of yellow to wine red. It soluble in ethanol, chloroform, dichloromethane, ethyl acetate, and ethyl ether, etc., insoluble in water.

Uses: The product is an important materials and intermediates of pharmaceuticals. As start material which mainly used in synthesis anticancer agent Goniofufurone, brain-tumor inhibitor 2-deoxy-2,2-difluoro-D-arabino-hexopyranose, activated precursors of oligonucleotides (9-(3'-O-benzyl-2'-O-benzyloxycarbonyl)β-D-xylofuranosyl) adenine, glycosidase inhibitor nojirimycin, HIV inhibitor 1,4-Dideoxy-1,4-imino-D-arabinitol, anti-inflammatory agent such as glycosylated indole, (-) - Dinemasone B, phosphatidyl-myo-inostiol mannoside analogues, and glycosylated asterosaponin with mult-pharmacological activities, etc.. It used in synthesis following pharmaceutica intermediate 2,4,6-tri-O-benzoyl-3-O-benzyl glucopyranosyl imidate for glucan-hexasaccharide vaccines, 3-O-benzyl-1,2-O-isopropylidene-α-L-idofuranose for Fondaparinux sodium, and 3-O-Benzyl-1,2-O-isopropylidene-α-xylo-pentodialdofuranose for anthracyclinone. The product also used in synthesis its following derivatives 3-O-benzyl-1,2-O-isopropylidene-D-glucofuranose, 3-O-benzyl-D-glucofuranose, α,β-D-Methyl glucopyranoside, 2,5, 6-tri-O-methyl-D-glucofuranose, 3-O-benzyl-xylitol, 3,4-di-O-methyl-D-erythritol, 2,4,6-Tri-O-methyl-D-mannose, L-idose, 6-deoxy-6-Acetamido-L-idothiapyranose, 6-O-benzoyl-l,2-O-isopropylidene-D-glucofuranose,3-O-benzyl-4,6-benzylidene-D-glucofuranose, 3-O-benzyl-1,2-isopropylidene-α-D-glucopyranoic acid, Methyl-3-O-Benzyl-5,6-di-O-isopropyIidene-α,β-D-glucofuranoside and so on. In addition, the product also is a kind of chiral auxiliary for some organicreaction and synthon for oligosaccharides and glycopolymer

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Founded in 2008, East Chemsources Limited is a professional manufacturer of supplier in food and pharmaceutical field in China.

Through more than four years development, QINGDAO EAST CHEMSOURCES TRADE CO.,LTD,there is new branch office Qingdao East Chemsources Limited,our company has developed from single product at first to providing solution to finished products now, is committed to providing solutions for success and growth through long term relationships.

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