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he UV absorber with CAS number 131-54-4 is 2,2' -dihydroxy-4,4' -dimethoxybenzophenone, also known as UV absorber UV-49 or BP-6125. Here are its details 12:

• Basic information

? Molecular formula:

? Molecular weight: 274.27

? EINECS number: 205-027-3

• Physical and chemical properties

? Appearance: Light yellow powder

? Melting point: ≥134℃

? Density: There is a specific density at 20 ° C, but the data do not clearly show the specific data, generally showing similar density characteristics to conventional benzophenone compounds

? Solubility: Soluble in some organic solvents, with oil-soluble characteristics

Pharmaceutical grade 2,2' -dihydroxy-4,4' -dimethoxybenzophenone (CAS No. 131-54-4) mainly has the following effects:

Pharmaceutical excipients

• Ultraviolet absorber: In some topical pharmaceutical preparations, such as creams, gels, lotions, etc., it can be used as an ultraviolet absorber, which can effectively absorb UVB and UVA bands in ultraviolet light, prevent the active ingredients in the drug from degrading and deteriorating due to ultraviolet radiation, so as to ensure the stability and effectiveness of the drug. For example, in some topical preparations containing easily oxidized components such as vitamin C, the addition of this substance can protect vitamin C from photooxidation.

• Photoprotectants: For some light-sensitive drugs, such as some antibiotics, biological products, etc., it can be added to drug packaging materials, such as plastic bottles, medicine bags, etc., to play a photoprotective role, reduce the impact of light on drugs, and extend the shelf life of drugs.

Potential therapeutic effects

• Antioxidant: The hydroxyl group and other groups in its structure make it have a certain antioxidant capacity. In some studies, it has been found that it may reduce oxidative stress response by removing excessive free radicals in the body, and has a potential adjuvant therapeutic effect on some diseases related to oxidative damage, such as cardiovascular diseases and neurodegenerative diseases.

• Anti-inflammatory: Some studies have shown that it may have a certain anti-inflammatory activity, can inhibit the release of inflammatory mediators and the activation of inflammation-related signaling pathways, and may have a certain therapeutic value for inflammatory diseases such as arthritis, dermatitis, etc., but the relevant research is still in the basic and clinical trial stage.

• Anti-skin aging: Due to its UV absorption and antioxidant properties, in the field of dermatology, it can be used in anti-skin aging research and applications. By reducing the damage of ultraviolet light to the skin, inhibiting the degradation of collagen and the damage of free radicals to skin cells, it helps to delay the appearance of aging phenomena such as skin wrinkles and sagging.